Browsing by Author "Kilicgun, Hasan"
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The Association of Plasminogen Activator Inhibitor Type 1 (PAI-1) Level and PAI-1 4G/5G Gene Polymorphism with the Formation and the Grade of Endometrial Cancer
Yildirim, Malik Ejder; Karakus, Savas; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Ersan, Serpil; Bakir, Sevtap (SPRINGER/PLENUM PUBLISHERS, 2017)Plasminogen activator inhibitor type 1 (PAI-1) is a serine protease inhibitor (Serpine 1), and it inhibits both tissue plasminogen activator and urokinase plasminogen activator which are important in fibrinolysis. We aimed ... -
A case of weill-marchesani syndrome with a novel mutation and vitamin d deficiency
Yildirim, Malik Ejder; Vural, Ayse; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Baser, Burak (DERMAN MEDICAL PUBL, 2018)Weill-Marchesani syndrome is an inherited connective tissue disorder. It is characterized by various ocular abnormalities and some skeletal problems. It is rarely seen in the world, but the clinical complications are ... -
A possible interaction o TIMP-1 and TSP-1 with familial mediterranean fever
Yildirim, Malik Ejder; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Bakir, Deniz; Ersan, Sepil (DERMAN MEDICAL PUBL, 2019)Aim: Matrix metalloproteinases (MMPs) may influence many biological and pathological processes including inflammatory responses. Thrombospondins (TSP) are a glycoprotein group of the extracellular matrix. In this study, ... -
Role of MTHFR gene polymorphisms, serum tissue inhibitor of metalloproteinases-1, thymus chemokine-1 and thrombospondin-1 in endometrial cancer
Yildirim, Malik Ejder; Kilicgun, Hasan; Kurtulgan, Hande Kucuk; Karakus, Savas; Ersan, Serpil; Bakir, Sevtap; Sezgin, Ilhan (E-CENTURY PUBLISHING CORP, 2016)The aim of this study was to evaluate the relationship between the MTHFR gene variants (677 C -> T and 1298 A -> C), serum tissue metalloproteinases inhibitor (TIMP-1), thrombospondin-1 (TSP-1), thymus chemokine-1 (TCK-1) ... -
Serum levels of polyamine synthesis enzymes increase in diabetic patients with breast cancer
Celik, V. Kenan; Kapancik, Sercan; Kacan, Turgut; Kacan, Selen Baloglu; Kapancik, Serkan; Kilicgun, Hasan (BIOSCIENTIFICA LTD, 2017)Background: In this study, it was aimed to investigate the relationship between diabetes and breast cancer and the detection of enzymes and ornithine levels in polyamine synthesis pathway in diabetes, breast cancer and ... -
Xanthine oxidase, adenosine deaminase and vitamin E levels in patients with schizophrenia
Kilicgun, Hasan; Ersan, Etem Erdal; Bakir, Sevtap; Ersan, Serpil; Koc, Derya; Demirpence, Ozlem; Dogan, Kubra (CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2016)Objective: Neuronal damage caused by free radicals is believed to be effective in pathogenesis of several psychiatric disorders. This belief is due to the toxic effects of free radicals that play a role in oxidative stress. ...